Photo by: Caitlin Abrams
Prof. Robert Vince featured on Mpls.StPaul Magazine
Life Saver: Robert Vince, a Minnesota superhero, creates drugs to combat diseases like AIDS and cancer.
Prof Wang Awarded NIH Grant
Congratulations to Prof. Zhengqiang Wang for being awarded a new 5 year grant by NIH
Structural studies of HIV Capsid with host factors and Capsid-targeting antivirals
Funding Agency: NIH/NIAID
Type: Multiple PI R01
PI(s): Stefan Sarafianos, PhD & Zhengqiang Wang, PhD
Research on Alzheimer's Disease by Prof Vince and Prof More Featured on C&EN News
Eye Test Might One Day Diagnose Alzheimer’s Before Symptoms Appear
Prof Swati More and Prof Robert Vince have developed a noninvasive imaging technique that tracks accumulation of the Alzheimer’s peptide, amyloid-β, in the eye. The pair have peered into the retinas of mice with their patented, microscope-based method, they hope to one day use it to identify Alzheimer’s disease in human patients years before symptoms manifest.
OakleyOriginals/CC 2.0/ flic.kr/p/5pjoeg
Prof Chen's Research on Parkinson’s Disease featured by the University
Drug Design for Parkinson’s Disease Starts Here
Recently, University of Minnesota Center for Drug Design member, organic chemist and assistant professor Prof Liqiang Chen, published a paper in the Journal of Medicinal Chemistry outlining the discovery of a potent and selective protein-inhibitor. Blocking the protein, Sirtuin 2 (SIRT2), also has the potential to block a primary contributor to Parkinson’s disease from causing harm.
Message from the Director
Robert Vince, PhD
The Center for Drug Design (CDD) was created to combine research and scholarship leading to the development of novel drugs for therapeutic applications, such as HIV, cancer, neurological diseases, dermatological agents, infectious diseases, novel processes, and medical devices. The Center for Drug Design combines the best of academic tradition along with an expectation of innovation and independence, and provides significant value for our academic and research community.
Department of Chemistry
University of Pennsylvania
Title: 'Single Electron Transformations to Enable Cross-Couplings'
The central theme of the Molander group's research is the development of new synthetic methods and their application to the synthesis of organic molecules. The group's focus is to expand and improve the Suzuki coupling reaction for organoboron compounds. Robust, air- and water-stable potassium organotrifluoroborates (R-BF3K), are employed to carry out couplings under relatively mild conditions using non-toxic components.
Date: December 16, 2015 Time: 10:30 - 11:30 AM Venue: TBA
Spotlight on Research
A faster acting and safer than existing options, an antidote for cyanide poisoning that works prophylactically to prevent or limit toxicity associated from exposure to cyanide has been developed.