Erin E. Carlson, PhD
University of Minnesota
Title: Chemical Probes for Histidine Kinase Protein Profiling and Inhibitor Discovery
The Carlson Group unites tools from chemistry and biology to promote the development and application of technologies that will contribute to the understanding of new strategies for treatment of bacterial infections and the discovery of efficacious compounds. Three complementary research directions are being pursued: (i) Protein Function – design and application of chemical probes for characterization of bacterial cell wall biosynthesis (ii) Target Exploration – generation of methods for the investigation and inhibition of histidine kinases (iii) Molecule Discovery – development of strategies to dramatically expand our ability to explore natural product chemical space.