Photo by Greta Kaul
Patently lucrative: the intellectual property that makes big money for the U
Compounds developed in Robert Vince’s University of Minnesota lab to combat the HIV virus made the University more than $600 million dollars. Read More
Patterson Group - Multiple Sclerosis
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) resulting in damage to the myelin or insulating covers in the brain and spinal cord. Read more about Patterson Group's efforts toward developing a treatment for MS: Click Here
Seeing Alzheimer's disease
A retinal scan technique, developed by researchers in the University’s Center for Drug Design (CDD), has the potential to detect AD in its early stages, when treatment may still be possible, and also to allow doctors to trace the progress of treatments and help the 100,000 Minnesotans with AD and their families. Read More
Photo by Ananya Mishra
UMN technology will aid Alzheimer's detection
Message from the Director
The Center for Drug Design (CDD) was created to combine research and scholarship leading to the development of novel drugs for therapeutic applications, such as HIV, cancer, neurological diseases, dermatological agents, infectious diseases, novel processes, and medical devices. The Center for Drug Design combines the best of academic tradition along with an expectation of innovation and independence, and provides significant value for our academic and research community.
Title: Identifying and Correcting Brain Circuit Dysfunction Associated with Autism
Using transgenic mice carrying autism-associated genetic mutations, Prof Rothwell's group has identified a very selective impairment of inhibitory synaptic transmission onto a genetically and anatomically defined brain cell type. This impairment of synaptic transmission causes specific forms of repetitive behavior in mice, which may be relevant to autism in humans. They are actively developing a novel pharmacotherapeutic strategy to compensate for the effects of these autism-associated genetic mutations, which may restore the normal function of brain circuits.